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Specifically, SIN may inhibit 7nAChR expression through the regulation of the ERK1/2/Egr-1 pathway (92), thereby suppressing M1 polarization and promoting a shift toward the M2 phenotype (105, 106)

Exploratory endpoints were assessed with descriptive statistics based on observed data

To apply for a TUE for cannabinoids, please visit the TUE application page and download the USADA TUE checklist and WADA guidelines under the Pain Management section

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